Cobiprostone
Catalog No. A66539

Cobiprostone is a type-2 chloride channel activator known for its protective effects against NSAID-induced cellular damage. It effectively prevents Indomethacin-induced depolarization of mitochondrial membrane potential and reverses subsequent loss of membrane integrity. This compound is valuable for research focused on mitochondrial function and cellular responsiveness to ion channel modulation.
Chemical Information
| Catalog Num | A66539 |
|---|---|
| M. Wt | 404.49 |
| Formula | C21H34F2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 333963-42-1 |
| Synonyms | SPI 8811 |
| SMILES | O=C(O)CCCCCC[C@H]([C@]1([H])[C@]2([H])O[C@@](O)(C(F)(F)C[C@@H](C)CC)CC1)C(C2)=O |
Biological Activity
| Description | Cobiprostone is a type-2 chloride channel activator known for its protective effects against NSAID-induced cellular damage. It effectively prevents Indomethacin-induced depolarization of mitochondrial membrane potential and reverses subsequent loss of membrane integrity. This compound is valuable for research focused on mitochondrial function and cellular responsiveness to ion channel modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


