Product Data Sheet
Alilusem potassium
Catalog No. A66549
Alilusem potassium is a selective chloride channel inhibitor known for its diuretic properties. Studies have demonstrated its effectiveness in reducing free water clearance while enhancing sodium and chloride excretion in urine during water diuresis in anesthetized canine models. Additionally, Alilusem potassium, when administered with Furosemide or Hydrochlorothiazide, further diminished free water clearance. This compound has also been shown to inhibit lumen-positive transepithelial voltage and chloride flux across isolated rabbit cortical thick ascending limbs of Henle, making it a valuable tool for research in renal physiology and electrolyte transport mechanisms.
Chemical Information
| Catalog Num | A66549 |
|---|---|
| M. Wt | 432.92 |
| Formula | C17H14ClKN2O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 114417-20-8 |
| Synonyms | M 17055 |
| SMILES | O=C(C1=CC=CC=C1C)N2CC/C(C3=C2C=C(C=C3)Cl)=N\OS(=O)(O[K])=O |
Biological Activity
| Description | Alilusem potassium is a selective chloride channel inhibitor known for its diuretic properties. Studies have demonstrated its effectiveness in reducing free water clearance while enhancing sodium and chloride excretion in urine during water diuresis in anesthetized canine models. Additionally, Alilusem potassium, when administered with Furosemide or Hydrochlorothiazide, further diminished free water clearance. This compound has also been shown to inhibit lumen-positive transepithelial voltage and chloride flux across isolated rabbit cortical thick ascending limbs of Henle, making it a valuable tool for research in renal physiology and electrolyte transport mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
