Product Data Sheet

LDN-212320

Catalog No. A66565

main product photo
LDN-212320 is a potent activator of the glutamate transporter GLT-1 (EAAT2), primarily functioning at the translational level. This compound is known to mitigate nociceptive pain by enhancing astroglial GLT-1 expression in both the hippocampus and anterior cingulate cortex. LDN-212320 is valuable in research focused on pain modulation and neuroprotection, offering insights into the role of glutamate transporters in neurological conditions.
Chemical Information
Catalog NumA66565
M. Wt293.39
FormulaC17H15N3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.894002-50-7
SynonymsLDN-0212320; OSU-0212320
SMILESCC1=CC=CC=C1CSC2=NN=C(C3=NC=CC=C3)C=C2
Biological Activity
DescriptionLDN-212320 is a potent activator of the glutamate transporter GLT-1 (EAAT2), primarily functioning at the translational level. This compound is known to mitigate nociceptive pain by enhancing astroglial GLT-1 expression in both the hippocampus and anterior cingulate cortex. LDN-212320 is valuable in research focused on pain modulation and neuroprotection, offering insights into the role of glutamate transporters in neurological conditions.
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