Product Data Sheet

DS2

Catalog No. A66651

main product photo
DS2 is a selective positive allosteric modulator of the δ-GABAA receptor. This compound specifically enhances GABAergic responses mediated by the α4β3δ receptor while exhibiting minimal activity at α4β3γ2 and α1β3γ2 receptors. DS2 demonstrates significant analgesic properties and holds potential for research in sleep disorders, making it a valuable tool in neuropharmacology studies.
Chemical Information
Catalog NumA66651
M. Wt353.83
FormulaC18H12ClN3OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.374084-31-8
Synonyms
SMILESO=C(NC1=C(C2=CC=CS2)N=C3C=CC=CN31)C4=CC=C(Cl)C=C4
Biological Activity
DescriptionDS2 is a selective positive allosteric modulator of the δ-GABAA receptor. This compound specifically enhances GABAergic responses mediated by the α4β3δ receptor while exhibiting minimal activity at α4β3γ2 and α1β3γ2 receptors. DS2 demonstrates significant analgesic properties and holds potential for research in sleep disorders, making it a valuable tool in neuropharmacology studies.
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