Product Data Sheet
TPMPA
Catalog No. A66669
TPMPA is a selective antagonist of the GABAC receptor, exhibiting a binding affinity of KB = 2.1 μM. It does not significantly interact with GABAA or GABAB receptors, with binding constants of KB = 320 μM and EC50 = 500 μM, respectively. This compound is valuable in research focused on modulating orientation selectivity in ganglion cells, making it an important tool for exploring neural signaling mechanisms.
Chemical Information
| Catalog Num | A66669 |
|---|---|
| M. Wt | 161.14 |
| Formula | C6H12NO2P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 182485-36-5 |
| Synonyms | |
| SMILES | O=P(C1=CCNCC1)(C)O |
Biological Activity
| Description | TPMPA is a selective antagonist of the GABAC receptor, exhibiting a binding affinity of KB = 2.1 μM. It does not significantly interact with GABAA or GABAB receptors, with binding constants of KB = 320 μM and EC50 = 500 μM, respectively. This compound is valuable in research focused on modulating orientation selectivity in ganglion cells, making it an important tool for exploring neural signaling mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
