Product Data Sheet
Pivagabine
Catalog No. A66677
Pivagabine is a GABA receptor antagonist that acts as a hydrophobic derivative of 4-aminobutyric acid, exhibiting significant neuromodulatory properties. This compound effectively crosses the blood-brain barrier in rodent models, demonstrating its potential for central nervous system research. Pivagabine antagonizes the neuroactive effects triggered by foot shock, influencing GABAA receptor function and modulating corticotropin-releasing factor (CRF) concentrations in the rat brain, thus making it a valuable tool in studies related to stress responses and anxiety.
Chemical Information
| Catalog Num | A66677 |
|---|---|
| M. Wt | 187.24 |
| Formula | C9H17NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 69542-93-4 |
| Synonyms | CXB-722 |
| SMILES | O=C(O)CCCNC(C(C)(C)C)=O |
Biological Activity
| Description | Pivagabine is a GABA receptor antagonist that acts as a hydrophobic derivative of 4-aminobutyric acid, exhibiting significant neuromodulatory properties. This compound effectively crosses the blood-brain barrier in rodent models, demonstrating its potential for central nervous system research. Pivagabine antagonizes the neuroactive effects triggered by foot shock, influencing GABAA receptor function and modulating corticotropin-releasing factor (CRF) concentrations in the rat brain, thus making it a valuable tool in studies related to stress responses and anxiety. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
