1-Phenyl-2-pyrrolidinone
Catalog No. A66685

1-Phenyl-2-pyrrolidinone is a phenyl analogue of gamma-aminobutyric acid (GABA) that exhibits sedative properties. It has been shown to reduce exploratory behavior in animal models, including rats at doses of 50-100 mg/kg (i.v.), and to inhibit emotional responses in dogs and cats. Additionally, 1-Phenyl-2-pyrrolidinone decreases pressor responses to emotional stress while not affecting the baroreceptor reflexes, making it a valuable tool for research on GABAergic signaling and emotional regulation.
Chemical Information
| Catalog Num | A66685 |
|---|---|
| M. Wt | 161.20 |
| Formula | C10H11NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4641-57-0 |
| Synonyms | 1-Phenylpyrrolidin-2-one |
| SMILES | C1=CC=C(C=C1)N2CCCC2=O |
Biological Activity
| Description | 1-Phenyl-2-pyrrolidinone is a phenyl analogue of gamma-aminobutyric acid (GABA) that exhibits sedative properties. It has been shown to reduce exploratory behavior in animal models, including rats at doses of 50-100 mg/kg (i.v.), and to inhibit emotional responses in dogs and cats. Additionally, 1-Phenyl-2-pyrrolidinone decreases pressor responses to emotional stress while not affecting the baroreceptor reflexes, making it a valuable tool for research on GABAergic signaling and emotional regulation. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


