Product Data Sheet
CGS 8216
Catalog No. A66697
CGS 8216 is a non-benzodiazepine ligand targeting the GABA receptor, exhibiting high affinity and specificity for rat forebrain membranes. This compound effectively inhibits 3H-flunitrazepam binding to rat synaptosomal membranes, demonstrating potent blocking of 3H-FLU labeling of brain benzodiazepine receptors in vivo, comparable to Diazepam. CGS 8216 is valuable for studying GABAergic signaling and the pharmacological properties of benzodiazepine receptors in neural research applications.
Chemical Information
| Catalog Num | A66697 |
|---|---|
| M. Wt | 261.28 |
| Formula | C16H11N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 77779-60-3 |
| Synonyms | |
| SMILES | O=C1N(C2=CC=CC=C2)N=C3C1=CNC4=C3C=CC=C4 |
Biological Activity
| Description | CGS 8216 is a non-benzodiazepine ligand targeting the GABA receptor, exhibiting high affinity and specificity for rat forebrain membranes. This compound effectively inhibits 3H-flunitrazepam binding to rat synaptosomal membranes, demonstrating potent blocking of 3H-FLU labeling of brain benzodiazepine receptors in vivo, comparable to Diazepam. CGS 8216 is valuable for studying GABAergic signaling and the pharmacological properties of benzodiazepine receptors in neural research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
