Product Data Sheet
(S)-Padsevonil
Catalog No. A66724
(S)-Padsevonil is the S-enantiomer of Padsevonil, a potent antiepileptic agent that selectively targets presynaptic and postsynaptic sites. This compound exhibits a high affinity for synaptic vesicular protein 2 (SV2), enhancing neurotransmitter release. Additionally, (S)-Padsevonil functions as a positive allosteric modulator and partial agonist of GABA receptors, demonstrating significant activity against α1 and α5 subtypes. Its efficacy has been established in various rodent models, making it a valuable tool for research into epilepsy and related neurological disorders.
Chemical Information
| Catalog Num | A66724 |
|---|---|
| M. Wt | 432.80 |
| Formula | C14H14ClF5N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1294001-37-8 |
| Synonyms | (S)-UCB-0942 |
| SMILES | O=C1N(C[C@H](CC(F)(F)Cl)C1)CC(N(N=C(COC)S2)C2=N3)=C3C(F)(F)F |
Biological Activity
| Description | (S)-Padsevonil is the S-enantiomer of Padsevonil, a potent antiepileptic agent that selectively targets presynaptic and postsynaptic sites. This compound exhibits a high affinity for synaptic vesicular protein 2 (SV2), enhancing neurotransmitter release. Additionally, (S)-Padsevonil functions as a positive allosteric modulator and partial agonist of GABA receptors, demonstrating significant activity against α1 and α5 subtypes. Its efficacy has been established in various rodent models, making it a valuable tool for research into epilepsy and related neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
