Product Data Sheet
Alpidem-d14
Catalog No. A66742
Alpidem-d14 is a stable isotope-labeled variant of Alpidem, a potent GABAA receptor ligand targeting the α1β2γ2 subunit with an IC50 of 17 nM. This compound is primarily investigated for its anxiolytic properties and influences various biological processes, including modulation of mitochondrial permeability and glutathione levels, leading to hepatocyte necrosis. Additionally, Alpidem-d14 is utilized in research focused on anxiety disorders, convulsive conditions, and the behavioral effects in stressed rodent models.
Chemical Information
| Catalog Num | A66742 |
|---|---|
| M. Wt | 418.42 |
| Formula | C21H9D14Cl2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189962-23-9 |
| Synonyms | |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C(CC1=C(C2=CC=C(C=C2)Cl)N=C3N1C=C(C=C3)Cl)=O |
Biological Activity
| Description | Alpidem-d14 is a stable isotope-labeled variant of Alpidem, a potent GABAA receptor ligand targeting the α1β2γ2 subunit with an IC50 of 17 nM. This compound is primarily investigated for its anxiolytic properties and influences various biological processes, including modulation of mitochondrial permeability and glutathione levels, leading to hepatocyte necrosis. Additionally, Alpidem-d14 is utilized in research focused on anxiety disorders, convulsive conditions, and the behavioral effects in stressed rodent models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
