Product Data Sheet
SCH 50911 hydrochloride
Catalog No. A66745
SCH 50911 hydrochloride is a selective, orally-active antagonist of the γ-Aminobutyric acid B (GABA(B)) receptor, exhibiting competitive binding with an IC50 value of 1.1 μM. This compound effectively antagonizes GABA(B) autoreceptors, leading to an increase in electrically-stimulated 3H overflow at an IC50 of 3 μM. SCH 50911 hydrochloride is utilized in research applications related to neuropharmacology, particularly in studying the modulation of synaptic transmission and the role of GABA(B) receptors in various neurological disorders.
Chemical Information
| Catalog Num | A66745 |
|---|---|
| M. Wt | 209.67 |
| Formula | C8H16ClNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 160415-07-6 |
| Synonyms | |
| SMILES | O=C(O)C[C@H]1CNC(C)(C)CO1.[H]Cl |
Biological Activity
| Description | SCH 50911 hydrochloride is a selective, orally-active antagonist of the γ-Aminobutyric acid B (GABA(B)) receptor, exhibiting competitive binding with an IC50 value of 1.1 μM. This compound effectively antagonizes GABA(B) autoreceptors, leading to an increase in electrically-stimulated 3H overflow at an IC50 of 3 μM. SCH 50911 hydrochloride is utilized in research applications related to neuropharmacology, particularly in studying the modulation of synaptic transmission and the role of GABA(B) receptors in various neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
