Product Data Sheet

CGP36216 hydrochloride

Catalog No. A66752

main product photo
CGP36216 hydrochloride is a selective antagonist of the GABAB receptor, exhibiting a Ki value of 0.3 μM. This compound effectively inhibits presynaptic GABA signaling, making it a useful tool for investigating the role of GABAB receptors in anxiety and trauma-related disorders. Research applications include studying synaptic transmission and evaluating therapeutic strategies for related neurological conditions.
Chemical Information
Catalog NumA66752
M. Wt187.60
FormulaC5H15ClNO2P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1781834-71-6
Synonyms
SMILESO=P(CC)(CCCN)O.Cl
Biological Activity
DescriptionCGP36216 hydrochloride is a selective antagonist of the GABAB receptor, exhibiting a Ki value of 0.3 μM. This compound effectively inhibits presynaptic GABA signaling, making it a useful tool for investigating the role of GABAB receptors in anxiety and trauma-related disorders. Research applications include studying synaptic transmission and evaluating therapeutic strategies for related neurological conditions.
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