Product Data Sheet
Baclofen-d5 hydrochloride
Catalog No. A66756
Baclofen-d5 hydrochloride is a deuterated analog of Baclofen, functioning as a selective agonist for the metabotropic GABAB receptor (GABABR). This compound closely mimics the action of γ-aminobutyric acid (GABA), facilitating slow presynaptic inhibition via GABAB signaling pathways. With its significant ability to penetrate the blood-brain barrier, Baclofen-d5 hydrochloride is valuable in studying muscle spasticity and related neurological conditions. Its stable isotope labeling further enhances its applications in metabolic and pharmacokinetic research.
Chemical Information
| Catalog Num | A66756 |
|---|---|
| M. Wt | 255.15 |
| Formula | C10H8D5Cl2NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2012598-58-0 |
| Synonyms | |
| SMILES | [2H]C(C(C(CN)([2H])CC(O)=O)=C([2H])C([2H])=C1Cl)=C1[2H].Cl |
Biological Activity
| Description | Baclofen-d5 hydrochloride is a deuterated analog of Baclofen, functioning as a selective agonist for the metabotropic GABAB receptor (GABABR). This compound closely mimics the action of γ-aminobutyric acid (GABA), facilitating slow presynaptic inhibition via GABAB signaling pathways. With its significant ability to penetrate the blood-brain barrier, Baclofen-d5 hydrochloride is valuable in studying muscle spasticity and related neurological conditions. Its stable isotope labeling further enhances its applications in metabolic and pharmacokinetic research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
