Product Data Sheet

Org20599

Catalog No. A66802

main product photo
Org20599 is a positive allosteric modulator and, at elevated concentrations, a direct agonist of the GABAA receptor, exhibiting an EC50 of 1.1 μM. This compound enhances GABAA receptor activity, contributing to the modulation of inhibitory neurotransmission. Org20599 is utilized in research exploring the effects of GABAergic signaling on various neurological conditions and for the investigation of anxiolytic and anticonvulsant properties.
Chemical Information
Catalog NumA66802
M. Wt438.04
FormulaC25H40ClNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.156685-94-8
Synonyms
SMILESC[C@@]12[C@@H](C(CCl)=O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)[C@@H](N5CCOCC5)C[C@]4(C)[C@@]3([H])CC2
Biological Activity
DescriptionOrg20599 is a positive allosteric modulator and, at elevated concentrations, a direct agonist of the GABAA receptor, exhibiting an EC50 of 1.1 μM. This compound enhances GABAA receptor activity, contributing to the modulation of inhibitory neurotransmission. Org20599 is utilized in research exploring the effects of GABAergic signaling on various neurological conditions and for the investigation of anxiolytic and anticonvulsant properties.
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SHIPPING AND STORAGE
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