Product Data Sheet
COR627
Catalog No. A66815
COR627 is a positive allosteric modulator of the GABA receptor, designed to enhance GABAergic activity. It increases the affinity for GABA(B) receptors, as demonstrated through its effects on both GABA and baclofen stimulation in rat cortical membranes. In vivo studies indicate that COR627 can amplify the sedative and hypnotic effects of baclofen, even at doses that are otherwise ineffective without pretreatment, making it a valuable tool for research in neuropharmacology and psychotropic drug studies.
Chemical Information
| Catalog Num | A66815 |
|---|---|
| M. Wt | 361.50 |
| Formula | C20H27NO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 329221-34-3 |
| Synonyms | |
| SMILES | O=C(OC)C1=C(SC(C)=C1CC)NC(C23CC4CC(CC(C3)C4)C2)=O |
Biological Activity
| Description | COR627 is a positive allosteric modulator of the GABA receptor, designed to enhance GABAergic activity. It increases the affinity for GABA(B) receptors, as demonstrated through its effects on both GABA and baclofen stimulation in rat cortical membranes. In vivo studies indicate that COR627 can amplify the sedative and hypnotic effects of baclofen, even at doses that are otherwise ineffective without pretreatment, making it a valuable tool for research in neuropharmacology and psychotropic drug studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
