Product Data Sheet

AZD 3043

Catalog No. A66843

main product photo
AZD 3043 is a positive allosteric modulator of GABA(A) receptors, demonstrating sedative and hypnotic activity. This compound enhances GABA(A) receptor-mediated chloride currents in vitro and produces hypnotic effects along with electroencephalographic inhibitory activity in vivo. Its unique esterase-dependent metabolic pathway results in a short duration of action, allowing for rapid clearance, which may offer potential clinical applications in managing sleep disorders.
Chemical Information
Catalog NumA66843
M. Wt351.44
FormulaC19H29NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.579494-66-9
SynonymsTHRX 918661
SMILESCCCOC(CC1=CC=C(OCC(N(CC)CC)=O)C(OCC)=C1)=O
Biological Activity
DescriptionAZD 3043 is a positive allosteric modulator of GABA(A) receptors, demonstrating sedative and hypnotic activity. This compound enhances GABA(A) receptor-mediated chloride currents in vitro and produces hypnotic effects along with electroencephalographic inhibitory activity in vivo. Its unique esterase-dependent metabolic pathway results in a short duration of action, allowing for rapid clearance, which may offer potential clinical applications in managing sleep disorders.
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SHIPPING AND STORAGE
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