Product Data Sheet
3α,21-Dihydroxy-5α-pregnan-20-one-d3
Catalog No. A66844
3α,21-Dihydroxy-5α-pregnan-20-one-d3 is a deuterium-labeled derivative of the neurosteroid 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), which acts as a positive modulator of GABAA receptors. This compound enhances the response of neurons to low concentrations of GABA, specifically at the α4β1δ subtype of GABAA receptors in vitro. It serves as a valuable stable isotope labeled reagent for research focusing on neurosteroid activity and GABAergic modulation.
Chemical Information
| Catalog Num | A66844 |
|---|---|
| M. Wt | 337.51 |
| Formula | C21H31D3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 203805-98-5 |
| Synonyms | THDOC-d3 |
| SMILES | C[C@@]12[C@](CC[C@]2([2H])C(C([2H])([2H])O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](C[C@@H](CC4)O)([H])CC3)C |
Biological Activity
| Description | 3α,21-Dihydroxy-5α-pregnan-20-one-d3 is a deuterium-labeled derivative of the neurosteroid 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), which acts as a positive modulator of GABAA receptors. This compound enhances the response of neurons to low concentrations of GABA, specifically at the α4β1δ subtype of GABAA receptors in vitro. It serves as a valuable stable isotope labeled reagent for research focusing on neurosteroid activity and GABAergic modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
