Product Data Sheet

3-Aminopropylphosphinic acid

Catalog No. A66846

main product photo
3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA) that acts as a potent and selective agonist of the GABAB receptor. Its primary mechanism involves enhancing GABAB receptor signaling, which is crucial for modulating inhibitory neurotransmission in the central nervous system. 3-APPA is valuable for research applications focused on neurological disorders, synaptic transmission, and the pharmacological functions of GABAB receptors.
Chemical Information
Catalog NumA66846
M. Wt123.09
FormulaC3H10NO2P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.103680-47-3
Synonyms3-APPA; CGP 27492; CGA 147823
SMILESO=P(CCCN)O
Biological Activity
Description3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA) that acts as a potent and selective agonist of the GABAB receptor. Its primary mechanism involves enhancing GABAB receptor signaling, which is crucial for modulating inhibitory neurotransmission in the central nervous system. 3-APPA is valuable for research applications focused on neurological disorders, synaptic transmission, and the pharmacological functions of GABAB receptors.
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