Product Data Sheet
Sodium bromide
Catalog No. A66868
Sodium bromide is a GABAergic system modulator that effectively reduces and blocks epileptiform discharges by enhancing inhibitory GABAergic functions. This compound increases the amplitude of inhibitory postsynaptic currents and paired-pulse inhibition, leading to pronounced anticonvulsant effects. Additionally, sodium bromide induces stimulation-induced extracellular alkalosis while sparing baseline pH levels and subsequent acidosis processes. It demonstrates species-specific pharmacokinetic characteristics and competes with chloride for renal tubular reabsorption, making it useful as a marker for extracellular fluid volume in research focused on epilepsy and related neurological conditions.
Chemical Information
| Catalog Num | A66868 |
|---|---|
| M. Wt | 102.89 |
| Formula | BrNa |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 7647-15-6 |
| Synonyms | NSC 77384; Sanibrom 40 |
| SMILES | [Na]Br |
Biological Activity
| Description | Sodium bromide is a GABAergic system modulator that effectively reduces and blocks epileptiform discharges by enhancing inhibitory GABAergic functions. This compound increases the amplitude of inhibitory postsynaptic currents and paired-pulse inhibition, leading to pronounced anticonvulsant effects. Additionally, sodium bromide induces stimulation-induced extracellular alkalosis while sparing baseline pH levels and subsequent acidosis processes. It demonstrates species-specific pharmacokinetic characteristics and competes with chloride for renal tubular reabsorption, making it useful as a marker for extracellular fluid volume in research focused on epilepsy and related neurological conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
