Product Data Sheet
Cholesteryl γ-aminobutyrate
Catalog No. A66871
Cholesteryl γ-aminobutyrate is a GABA-mimetic prodrug that targets GABA receptors in the central nervous system. It effectively inhibits orthodromically-evoked discharges in pyramidal cells located in the CA1 region of the hippocampus. This compound demonstrates dose-dependent suppression of locomotor activity in rodents and has been shown to inhibit Bicuculline-induced seizures in mice. Cholesteryl γ-aminobutyrate is valuable for research into CNS disorders associated with dysfunctional GABAergic signaling.
Chemical Information
| Catalog Num | A66871 |
|---|---|
| M. Wt | 471.76 |
| Formula | C31H53NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 89210-68-4 |
| Synonyms | |
| SMILES | C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCN)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C |
Biological Activity
| Description | Cholesteryl γ-aminobutyrate is a GABA-mimetic prodrug that targets GABA receptors in the central nervous system. It effectively inhibits orthodromically-evoked discharges in pyramidal cells located in the CA1 region of the hippocampus. This compound demonstrates dose-dependent suppression of locomotor activity in rodents and has been shown to inhibit Bicuculline-induced seizures in mice. Cholesteryl γ-aminobutyrate is valuable for research into CNS disorders associated with dysfunctional GABAergic signaling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
