Product Data Sheet
Lorotomidate
Catalog No. A66874
Lorotomidate is a GABAA receptor agonist known for its anesthetic properties, exhibiting an ED50 of 2 mg/kg intravenously in KM mice, while demonstrating an LD50 of 46.5 mg/kg in the same model. This compound’s unique profile includes the ability to maintain corticosteroid secretion, which highlights its safety and efficacy. Lorotomidate is utilized in research to explore anesthetic mechanisms and neuro pharmacology, contributing to studies aimed at understanding GABAA receptor modulation.
Chemical Information
| Catalog Num | A66874 |
|---|---|
| M. Wt | 262.28 |
| Formula | C14H15FN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2093287-60-4 |
| Synonyms | |
| SMILES | C[C@H](C1=CC=CC=C1)N2C(C(OCC)=O)=C(N=C2)F |
Biological Activity
| Description | Lorotomidate is a GABAA receptor agonist known for its anesthetic properties, exhibiting an ED50 of 2 mg/kg intravenously in KM mice, while demonstrating an LD50 of 46.5 mg/kg in the same model. This compound’s unique profile includes the ability to maintain corticosteroid secretion, which highlights its safety and efficacy. Lorotomidate is utilized in research to explore anesthetic mechanisms and neuro pharmacology, contributing to studies aimed at understanding GABAA receptor modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
