Product Data Sheet
2-AEMP
Catalog No. A66887
2-AEMP (2-Aminoethyl methylphosphonate) functions as an antagonist of the GABA(A)-ρ1 receptor. It demonstrates competitive inhibition with an IC(50) value of 18 μM, which is substantially less potent than the 7 μM seen with TPMPA. Notably, 2-AEMP exhibits a higher release rate of inhibition upon termination compared to TPMPA. Additionally, this compound requires a shorter preincubation time to achieve its inhibitory effects, making it a valuable tool for research on GABA receptor modulation and related neurological studies.
Chemical Information
| Catalog Num | A66887 |
|---|---|
| M. Wt | 139.09 |
| Formula | C3H10NO3P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 321882-95-5 |
| Synonyms | 2-Aminoethyl methylphosphonate |
| SMILES | CP(OCCN)(O)=O |
Biological Activity
| Description | 2-AEMP (2-Aminoethyl methylphosphonate) functions as an antagonist of the GABA(A)-ρ1 receptor. It demonstrates competitive inhibition with an IC(50) value of 18 μM, which is substantially less potent than the 7 μM seen with TPMPA. Notably, 2-AEMP exhibits a higher release rate of inhibition upon termination compared to TPMPA. Additionally, this compound requires a shorter preincubation time to achieve its inhibitory effects, making it a valuable tool for research on GABA receptor modulation and related neurological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
