Product Data Sheet
Emamectin B1a
Catalog No. A66919
Emamectin B1a is a semisynthetic derivative of avermectin B1a that serves as a GABA receptor activator. It enhances GABA responses by binding to GABAA receptors, demonstrating IC50 values of 57 nM for α1β1γ2, 210 nM for α1β2γ2, and 49.8 nM for α1β3γ2. Additionally, Emamectin B1a interacts with glycine receptors, exhibiting an IC50 of 218 nM in rat spinal cord. Its potent activity is evident in pest control applications, achieving 90% mortality in S. exigua larvae at concentrations as low as 1.067 ng/mL in foliar spray bioassays and topical applications.
Chemical Information
| Catalog Num | A66919 |
|---|---|
| M. Wt | 886.12 |
| Formula | C49H75NO13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 121124-29-6 |
| Synonyms | L-656,748 |
| SMILES | CC[C@@H]([C@@H]1[C@@H](C)C=C[C@]2(C[C@@H]3C[C@@H](C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@H](NC)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6CO[C@H]7[C@]\6(O)[C@H](C(O3)=O)C=C(C)[C@H]7O)O2)O1)C |
Biological Activity
| Description | Emamectin B1a is a semisynthetic derivative of avermectin B1a that serves as a GABA receptor activator. It enhances GABA responses by binding to GABAA receptors, demonstrating IC50 values of 57 nM for α1β1γ2, 210 nM for α1β2γ2, and 49.8 nM for α1β3γ2. Additionally, Emamectin B1a interacts with glycine receptors, exhibiting an IC50 of 218 nM in rat spinal cord. Its potent activity is evident in pest control applications, achieving 90% mortality in S. exigua larvae at concentrations as low as 1.067 ng/mL in foliar spray bioassays and topical applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
