Product Data Sheet
GMQ
Catalog No. A66941
GMQ is a competitive antagonist of the GABAergic receptor, primarily targeting the GABA(A) receptor subtypes α1β2, α1β2γ2, α4β2γ2, and α5β2γ2. This compound potently inhibits GABAAR activity, enhancing neuronal excitation by disrupting GABAergic transmission. Additionally, GMQ offers anti-histaminic effects within the enteric system, specifically inhibiting gastric acid secretion, making it valuable for research in neuropharmacology and gastrointestinal function.
Chemical Information
| Catalog Num | A66941 |
|---|---|
| M. Wt | 201.23 |
| Formula | C10H11N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 716-11-0 |
| Synonyms | 2-Guanidine-4-methylquinazoline |
| SMILES | NC(NC1=NC(C)=C2C=CC=CC2=N1)=N |
Biological Activity
| Description | GMQ is a competitive antagonist of the GABAergic receptor, primarily targeting the GABA(A) receptor subtypes α1β2, α1β2γ2, α4β2γ2, and α5β2γ2. This compound potently inhibits GABAAR activity, enhancing neuronal excitation by disrupting GABAergic transmission. Additionally, GMQ offers anti-histaminic effects within the enteric system, specifically inhibiting gastric acid secretion, making it valuable for research in neuropharmacology and gastrointestinal function. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
