Product Data Sheet

Ivabradine

Catalog No. A67042

main product photo
Ivabradine is a potent HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that selectively inhibits the cardiac pacemaker current (If). This compound effectively reduces heart rate in a dose-dependent manner without affecting blood pressure. In addition to its use in cardiovascular research, Ivabradine exhibits anticonvulsant, anti-ischemic, and anti-anginal properties, making it valuable for diverse biological investigations.
Chemical Information
Catalog NumA67042
M. Wt468.59
FormulaC27H36N2O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.155974-00-8
Synonyms
SMILESO=C1N(CCCN(C[C@@H]2C3=CC(OC)=C(OC)C=C3C2)C)CCC4=CC(OC)=C(OC)C=C4C1
Biological Activity
DescriptionIvabradine is a potent HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that selectively inhibits the cardiac pacemaker current (If). This compound effectively reduces heart rate in a dose-dependent manner without affecting blood pressure. In addition to its use in cardiovascular research, Ivabradine exhibits anticonvulsant, anti-ischemic, and anti-anginal properties, making it valuable for diverse biological investigations.
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SHIPPING AND STORAGE
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