Product Data Sheet

HCN2 modulator-6

Catalog No. A67054

main product photo
HCN2 modulator-6 is a potent inhibitor of the HCN2 ion channel, exhibiting an IC50 of 7 nM. This compound effectively suppresses HCN2 channel activity, making it a valuable tool for investigating mechanisms underlying pain, including inflammatory and neuropathic pain. Additionally, HCN2 modulator-6 is applicable in research focused on tinnitus, central nervous system disorders, psychiatric conditions, and mood disorders.
Chemical Information
Catalog NumA67054
M. Wt455.46
FormulaC21H18FN5O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3080809-10-2
Synonyms
SMILESO=C(C1=CC=NS1)NC2=NN(CC(C)OC)C3=NC=C(C4=CC5=C(OCO5)C(F)=C4)C=C23
Biological Activity
DescriptionHCN2 modulator-6 is a potent inhibitor of the HCN2 ion channel, exhibiting an IC50 of 7 nM. This compound effectively suppresses HCN2 channel activity, making it a valuable tool for investigating mechanisms underlying pain, including inflammatory and neuropathic pain. Additionally, HCN2 modulator-6 is applicable in research focused on tinnitus, central nervous system disorders, psychiatric conditions, and mood disorders.
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