Product Data Sheet
KIO-301
Catalog No. A67055
KIO-301 is a photoswitchable blocker of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound serves as a versatile tool for research in retinal diseases, specifically targeting the reactivation of HCN channels in models of retinitis pigmentosa. Its ability to be controlled by light makes it particularly useful for studies requiring precise spatiotemporal modulation of channel activity.
Chemical Information
| Catalog Num | A67055 |
|---|---|
| M. Wt | 552.55 |
| Formula | C29H38BrN5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1643463-61-9 |
| Synonyms | |
| SMILES | O=C(C[N+](CC)(CC)CC)NC1=CC=C(C=C1)/N=N/C2=CC=C(N(CC)CC3=CC=CC=C3)C=C2.[Br-] |
Biological Activity
| Description | KIO-301 is a photoswitchable blocker of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound serves as a versatile tool for research in retinal diseases, specifically targeting the reactivation of HCN channels in models of retinitis pigmentosa. Its ability to be controlled by light makes it particularly useful for studies requiring precise spatiotemporal modulation of channel activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
