Product Data Sheet

EMD-95885

Catalog No. A67138

main product photo
EMD-95885 is a selective antagonist of the NR2B subunit of NMDA receptors, exhibiting an IC50 of 3.9 nM. This specificity enables EMD-95885 to effectively block NR2B-containing NMDA receptor activity without engaging other binding sites on the receptor. It is valuable for research focusing on neurobiology, synaptic plasticity, and the mechanisms underlying neurological disorders.
Chemical Information
Catalog NumA67138
M. Wt382.43
FormulaC22H23FN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.178165-43-0
Synonyms
SMILESO=C1OC2=CC(C(CCN3CCC(CC3)CC4=CC=C(C=C4)F)=O)=CC=C2N1
Biological Activity
DescriptionEMD-95885 is a selective antagonist of the NR2B subunit of NMDA receptors, exhibiting an IC50 of 3.9 nM. This specificity enables EMD-95885 to effectively block NR2B-containing NMDA receptor activity without engaging other binding sites on the receptor. It is valuable for research focusing on neurobiology, synaptic plasticity, and the mechanisms underlying neurological disorders.
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