Product Data Sheet
(Rac)-Lanicemine
Catalog No. A67152
(Rac)-Lanicemine is a potent NMDA receptor antagonist that functions as a low-trapping blocker of NMDA channels, exhibiting a Ki value between 0.56-2.1 μM. This compound demonstrates antidepressant properties, supported by IC50 values of 4-7 μM in CHO cells and 6.4 μM in Xenopus oocyte cells. Its unique pharmacological profile makes (Rac)-Lanicemine valuable for research investigating the mechanisms of depression and the role of NMDA receptors in neuropsychiatric disorders.
Chemical Information
| Catalog Num | A67152 |
|---|---|
| M. Wt | 198.27 |
| Formula | C13H14N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 61890-25-3 |
| Synonyms | (Rac)-AZD6765 |
| SMILES | NC(C1=CC=CC=C1)CC2=NC=CC=C2 |
Biological Activity
| Description | (Rac)-Lanicemine is a potent NMDA receptor antagonist that functions as a low-trapping blocker of NMDA channels, exhibiting a Ki value between 0.56-2.1 μM. This compound demonstrates antidepressant properties, supported by IC50 values of 4-7 μM in CHO cells and 6.4 μM in Xenopus oocyte cells. Its unique pharmacological profile makes (Rac)-Lanicemine valuable for research investigating the mechanisms of depression and the role of NMDA receptors in neuropsychiatric disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
