Product Data Sheet
TP-050
Catalog No. A67211
TP-050 is a potent, orally active NMDAR agonist, selectively targeting the GluN2A and GluN2D subtypes with EC50 values of 0.51 μM and 9.6 μM, respectively. This compound effectively crosses the blood-brain barrier, facilitating its role in enhancing hippocampal long-term potentiation and promoting neuronal signal transmission. TP-050 offers valuable applications in neuroscience research, particularly in studies involving synaptic plasticity and cognitive function.
Chemical Information
| Catalog Num | A67211 |
|---|---|
| M. Wt | 380.78 |
| Formula | C16H15ClF2N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3085030-47-0 |
| Synonyms | |
| SMILES | CC1=CN(C(C2=CC(CN3N=C(C=C3Cl)C(F)F)=NN12)=O)[C@@H](CC#N)C |
Biological Activity
| Description | TP-050 is a potent, orally active NMDAR agonist, selectively targeting the GluN2A and GluN2D subtypes with EC50 values of 0.51 μM and 9.6 μM, respectively. This compound effectively crosses the blood-brain barrier, facilitating its role in enhancing hippocampal long-term potentiation and promoting neuronal signal transmission. TP-050 offers valuable applications in neuroscience research, particularly in studies involving synaptic plasticity and cognitive function. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
