Product Data Sheet
JNJ-56022486
Catalog No. A67212
JNJ-56022486 is a potent negative modulator of the AMPA receptor, exhibiting a Ki value of 19 nM and selective antagonism for TARP-γ8. This compound demonstrates effective blood-brain barrier permeability, making it suitable for in vivo studies. JNJ-56022486 is primarily utilized in research focused on epilepsy and related neurological disorders, providing a valuable tool for investigating synaptic transmission and excitability in the central nervous system.
Chemical Information
| Catalog Num | A67212 |
|---|---|
| M. Wt | 283.71 |
| Formula | C15H10ClN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2036082-79-6 |
| Synonyms | |
| SMILES | N#CCC1=CC=CC(Cl)=C1C2=CC=C(N3)C(NC3=O)=C2 |
Biological Activity
| Description | JNJ-56022486 is a potent negative modulator of the AMPA receptor, exhibiting a Ki value of 19 nM and selective antagonism for TARP-γ8. This compound demonstrates effective blood-brain barrier permeability, making it suitable for in vivo studies. JNJ-56022486 is primarily utilized in research focused on epilepsy and related neurological disorders, providing a valuable tool for investigating synaptic transmission and excitability in the central nervous system. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
