Product Data Sheet
(3S,6R)-NML
Catalog No. A67243
(3S,6R)-NML is an NMDA receptor antagonist that demonstrates pIC50 values of 4.8 for GluN1-GluN2A, 4.6 for GluN1-GluN2B, and 5.0 for both GluN1-GluN2C and GluN1-GluN2D. This compound is instrumental in studying the role of NMDA receptors in neurological disorders, particularly in depression research. Its specific antagonistic properties make it a valuable tool for investigating synaptic plasticity and related therapeutic approaches.
Chemical Information
| Catalog Num | A67243 |
|---|---|
| M. Wt | 297.43 |
| Formula | C20H27NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1585965-04-3 |
| Synonyms | |
| SMILES | CC[C@H](O)C(C1=CC=CC=C1)(C2=CC=CC=C2)C[C@H](NC)C |
Biological Activity
| Description | (3S,6R)-NML is an NMDA receptor antagonist that demonstrates pIC50 values of 4.8 for GluN1-GluN2A, 4.6 for GluN1-GluN2B, and 5.0 for both GluN1-GluN2C and GluN1-GluN2D. This compound is instrumental in studying the role of NMDA receptors in neurological disorders, particularly in depression research. Its specific antagonistic properties make it a valuable tool for investigating synaptic plasticity and related therapeutic approaches. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
