Product Data Sheet
LY 215490
Catalog No. A67262
LY 215490 is a selective, competitive antagonist of the AMPA receptor, exhibiting inhibitory potency with IC50 values of 4.8 μM against AMPA, 26.4 μM against CGS 19755, and 247 μM against kainate. This compound demonstrates neuroprotective effects, particularly in the context of focal ischaemia. LY 215490 serves as a valuable tool in studying excitatory neurotransmission and its implications in neurodegenerative diseases.
Chemical Information
| Catalog Num | A67262 |
|---|---|
| M. Wt | 279.34 |
| Formula | C13H21N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 150010-68-7 |
| Synonyms | |
| SMILES | OC([C@@H](C1)NC[C@](CC2)([H])[C@@]1([H])C[C@@H]2CCC3=NN=NN3)=O |
Biological Activity
| Description | LY 215490 is a selective, competitive antagonist of the AMPA receptor, exhibiting inhibitory potency with IC50 values of 4.8 μM against AMPA, 26.4 μM against CGS 19755, and 247 μM against kainate. This compound demonstrates neuroprotective effects, particularly in the context of focal ischaemia. LY 215490 serves as a valuable tool in studying excitatory neurotransmission and its implications in neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
