Product Data Sheet

NMDA receptor potentiator-1

Catalog No. A67289

main product photo
NMDA receptor potentiator-1 is a selective modulator targeting the NMDA receptor, specifically enhancing the activity of NR2C and NR2D subunits with IC50 values of 4 μM and 5 μM, respectively. This compound shows promise in increasing synaptic transmission and may serve as a valuable tool in studies related to neuropharmacology, synaptic plasticity, and neurodegenerative diseases. Its selective mechanism of action makes it a suitable candidate for investigating receptor-specific pathways and potential therapeutic applications.
Chemical Information
Catalog NumA67289
M. Wt467.94
FormulaC26H26ClNO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.486427-18-3
Synonyms
SMILESO=C(N1CCC2=CC(OC)=C(C=C2C1COC3=CC=C(C=C3)OC)OC)C4=CC=C(C=C4)Cl
Biological Activity
DescriptionNMDA receptor potentiator-1 is a selective modulator targeting the NMDA receptor, specifically enhancing the activity of NR2C and NR2D subunits with IC50 values of 4 μM and 5 μM, respectively. This compound shows promise in increasing synaptic transmission and may serve as a valuable tool in studies related to neuropharmacology, synaptic plasticity, and neurodegenerative diseases. Its selective mechanism of action makes it a suitable candidate for investigating receptor-specific pathways and potential therapeutic applications.
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