L-703717
Catalog No. A67300

L-703717 is a selective NMDA receptor antagonist that preferentially binds to cerebellar-specific NMDA receptors featuring the GluRepsilon3 subunit. This compound exhibits prominent accumulation in the rodent cerebellum, making it a valuable tool for investigating neurological diseases. Its unique selectivity and mechanism of action facilitate research into the underlying mechanisms of neurotransmission and potential therapeutic targets in neurological disorders.
Chemical Information
| Catalog Num | A67300 |
|---|---|
| M. Wt | 391.85 |
| Formula | C23H18ClNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 142326-92-9 |
| Synonyms | |
| SMILES | OC1=C(C2=CC(CC3=CC=C(OC)C=C3)=CC=C2)C(NC4=CC(Cl)=CC=C14)=O |
Biological Activity
| Description | L-703717 is a selective NMDA receptor antagonist that preferentially binds to cerebellar-specific NMDA receptors featuring the GluRepsilon3 subunit. This compound exhibits prominent accumulation in the rodent cerebellum, making it a valuable tool for investigating neurological diseases. Its unique selectivity and mechanism of action facilitate research into the underlying mechanisms of neurotransmission and potential therapeutic targets in neurological disorders. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


