Product Data Sheet
UBP-282
Catalog No. A67330
UBP-282 is a potent and selective competitive antagonist of AMPA and kainate receptors. It effectively inhibits the fast component of the dorsal root-evoked ventral root potential (fDR-VRP) with an IC50 value of 10.3 μM. In addition, UBP-282 antagonizes kainate-induced depolarizations of dorsal roots, exhibiting a pA2 value of 4.96. This compound serves as a valuable tool for investigating excitatory neurotransmission and related neurological pathways.
Chemical Information
| Catalog Num | A67330 |
|---|---|
| M. Wt | 333.30 |
| Formula | C15H15N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 544697-47-4 |
| Synonyms | |
| SMILES | O=C(O)[C@@H](N)CN(C(N1CC2=CC=C(C(O)=O)C=C2)=O)C=CC1=O |
Biological Activity
| Description | UBP-282 is a potent and selective competitive antagonist of AMPA and kainate receptors. It effectively inhibits the fast component of the dorsal root-evoked ventral root potential (fDR-VRP) with an IC50 value of 10.3 μM. In addition, UBP-282 antagonizes kainate-induced depolarizations of dorsal roots, exhibiting a pA2 value of 4.96. This compound serves as a valuable tool for investigating excitatory neurotransmission and related neurological pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
