Product Data Sheet
Perfluoroenanthic acid-13C4
Catalog No. A67354
Perfluoroenanthic acid-13C4 is a stable isotope labeled variant of Perfluoroenanthic acid, a perfluoroalkyl substance (PFAS) known for its significant biological implications. This compound has been shown to adversely affect the development of seminiferous tubules and influence m6A RNA methylation in the testes of offspring mice following maternal exposure, which disrupts spermatogenesis and contributes to reproductive toxicity. Additionally, Perfluoroenanthic acid alters dendritic spine morphology and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity, synaptic transmission, and elevating the expression of key excitatory synapse-related proteins, such as Synaptophysin and PSD95, making it valuable for research in neurobiology and developmental toxicology.
Chemical Information
| Catalog Num | A67354 |
|---|---|
| M. Wt | 368.03 |
| Formula | C313C4HF13O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2328024-55-9 |
| Synonyms | Perfluoroheptanoic acid-13C4; Tridecafluoroheptanoic acid-13C4; PFHpA-13C4 |
| SMILES | FC(F)(F)C(F)(F)C(F)(F)[13C](F)(F)[13C](F)(F)[13C](F)(F)[13C](O)=O |
Biological Activity
| Description | Perfluoroenanthic acid-13C4 is a stable isotope labeled variant of Perfluoroenanthic acid, a perfluoroalkyl substance (PFAS) known for its significant biological implications. This compound has been shown to adversely affect the development of seminiferous tubules and influence m6A RNA methylation in the testes of offspring mice following maternal exposure, which disrupts spermatogenesis and contributes to reproductive toxicity. Additionally, Perfluoroenanthic acid alters dendritic spine morphology and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity, synaptic transmission, and elevating the expression of key excitatory synapse-related proteins, such as Synaptophysin and PSD95, making it valuable for research in neurobiology and developmental toxicology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
