Product Data Sheet

Conantokin G

Catalog No. A67363

main product photo
Conantokin G is a 17-amino-acid peptide that acts as a potent and selective competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. It effectively inhibits NMDA-evoked currents in murine cortical neurons with an IC50 value of 480 nM. This compound exhibits neuroprotective properties, making it valuable for research in neurobiology and the study of excitotoxicity.
Chemical Information
Catalog NumA67363
M. Wt2264.19
FormulaC88H138N26O44
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.93438-65-4
Synonyms
SMILES[C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CCC(O)=O)=O)CC(C(O)=O)C(O)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CO)=O)CCCCN)=O)CC(C(O)=O)C(O)=O)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(C(O)=O)C(O)=O)=O)CCC(N)=O)=O)CC(N)=O)=O)CC(C(O)=O)C(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C(O)=O)C(O)=O
Biological Activity
DescriptionConantokin G is a 17-amino-acid peptide that acts as a potent and selective competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. It effectively inhibits NMDA-evoked currents in murine cortical neurons with an IC50 value of 480 nM. This compound exhibits neuroprotective properties, making it valuable for research in neurobiology and the study of excitotoxicity.
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SHIPPING AND STORAGE
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