Product Data Sheet
(S)-CPW 399
Catalog No. A67367
(S)-CPW 399 is a subtype-selective full agonist of AMPA receptors, demonstrating a 20-fold higher affinity for GluA1 and GluA2 subunits compared to GluA3 and GluA4 subunits. By activating AMPA receptors with GluA1 subunits, (S)-CPW 399 significantly enhances the spontaneous firing rate of locus coeruleus noradrenergic neurons. This compound is valuable for research into neurological diseases, providing insights into synaptic transmission and neuronal excitability.
Chemical Information
| Catalog Num | A67367 |
|---|---|
| M. Wt | 239.23 |
| Formula | C10H13N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 389888-02-2 |
| Synonyms | |
| SMILES | OC([C@@H](N)CN1C2=C(CCC2)C(NC1=O)=O)=O |
Biological Activity
| Description | (S)-CPW 399 is a subtype-selective full agonist of AMPA receptors, demonstrating a 20-fold higher affinity for GluA1 and GluA2 subunits compared to GluA3 and GluA4 subunits. By activating AMPA receptors with GluA1 subunits, (S)-CPW 399 significantly enhances the spontaneous firing rate of locus coeruleus noradrenergic neurons. This compound is valuable for research into neurological diseases, providing insights into synaptic transmission and neuronal excitability. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
