Product Data Sheet
GYKI-47261 dihydrochloride
Catalog No. A67384
GYKI-47261 dihydrochloride is a selective, orally active antagonist of the AMPA receptor, exhibiting an IC50 of 2.5 μM. This compound demonstrates a wide range of anticonvulsive activity and offers neuroprotective effects, making it valuable for neurological research. Additionally, GYKI-47261 serves as a potent inducer of the cytochrome P450 enzyme CYP2E1, further expanding its potential applications in pharmacological studies.
Chemical Information
| Catalog Num | A67384 |
|---|---|
| M. Wt | 395.71 |
| Formula | C18H17Cl3N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217049-32-5 |
| Synonyms | |
| SMILES | NC1=CC=C(C2=NN3C(CC4=CC=C(Cl)C=C42)=NC(C)=C3)C=C1.[H]Cl.[H]Cl |
Biological Activity
| Description | GYKI-47261 dihydrochloride is a selective, orally active antagonist of the AMPA receptor, exhibiting an IC50 of 2.5 μM. This compound demonstrates a wide range of anticonvulsive activity and offers neuroprotective effects, making it valuable for neurological research. Additionally, GYKI-47261 serves as a potent inducer of the cytochrome P450 enzyme CYP2E1, further expanding its potential applications in pharmacological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
