Product Data Sheet
Philanthotoxin 74 diTFA
Catalog No. A67419
Philanthotoxin 74 diTFA is a selective AMPA receptor antagonist, primarily targeting the GluR3 and GluR1 subunits with IC50 values of 263 nM and 296 nM, respectively. This compound is instrumental in studies focused on synaptic transmission and neuropharmacology, providing valuable insights into excitatory neurotransmission and potential therapeutic interventions for neurological disorders. Its specificity makes it a useful tool for researchers investigating the role of AMPA receptors in various biological contexts.
Chemical Information
| Catalog Num | A67419 |
|---|---|
| M. Wt | 662.66 |
| Formula | C28H44F6N4O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 401601-12-5 |
| Synonyms | PhTx 74 diTFA |
| SMILES | O=C(NCCCCCCCNCCCCN)[C@@H](NC(CCC)=O)CC1=CC=C(O)C=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F |
Biological Activity
| Description | Philanthotoxin 74 diTFA is a selective AMPA receptor antagonist, primarily targeting the GluR3 and GluR1 subunits with IC50 values of 263 nM and 296 nM, respectively. This compound is instrumental in studies focused on synaptic transmission and neuropharmacology, providing valuable insights into excitatory neurotransmission and potential therapeutic interventions for neurological disorders. Its specificity makes it a useful tool for researchers investigating the role of AMPA receptors in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
