Product Data Sheet
(R,S,S)-Dihydrotetrabenazine
Catalog No. A67451
(R,S,S)-Dihydrotetrabenazine is a secondary alcohol metabolite derived from Tetrabenazine, functioning primarily as a poor inhibitor of the vesicular monoamine transporter 2 (VMAT2) with a Ki value of 690 nM. This compound is utilized in neuropharmacological studies to investigate the modulation of monoamine transporters and their role in diseases such as Parkinson's and Huntington's. Its unique isomeric structure allows for in-depth research into the pharmacokinetics and pharmacodynamics of related compounds.
Chemical Information
| Catalog Num | A67451 |
|---|---|
| M. Wt | 319.44 |
| Formula | C19H29NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 924854-62-6 |
| Synonyms | R,S,S-DHTBZ |
| SMILES | [H][C@@]12C[C@H]([C@H](CN1CCC3=C2C=C(C(OC)=C3)OC)CC(C)C)O |
Biological Activity
| Description | (R,S,S)-Dihydrotetrabenazine is a secondary alcohol metabolite derived from Tetrabenazine, functioning primarily as a poor inhibitor of the vesicular monoamine transporter 2 (VMAT2) with a Ki value of 690 nM. This compound is utilized in neuropharmacological studies to investigate the modulation of monoamine transporters and their role in diseases such as Parkinson's and Huntington's. Its unique isomeric structure allows for in-depth research into the pharmacokinetics and pharmacodynamics of related compounds. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
