Product Data Sheet

AR-C141990 hydrochloride

Catalog No. A67487

main product photo
AR-C141990 hydrochloride is a selective inhibitor of monocarboxylate transporters (MCTs), specifically demonstrating pKi values of 7.6 and 6.6 for MCT-1 and MCT-2, respectively. This compound exhibits immunosuppressive properties and is utilized in research concerning graft versus host disease and metabolic regulation. Its ability to modulate lactate transport makes it a valuable tool for studying the role of MCTs in various biological processes.
Chemical Information
Catalog NumA67487
M. Wt529.05
FormulaC26H29ClN4O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2250019-94-2
Synonyms
SMILESO=C1N(CC(C)C)C2=C(C(C(N3C[C@H](O)CC3)=O)=C(CC4=CC=NC5=CC=CC=C45)S2)C(N1C)=O.[H]Cl
Biological Activity
DescriptionAR-C141990 hydrochloride is a selective inhibitor of monocarboxylate transporters (MCTs), specifically demonstrating pKi values of 7.6 and 6.6 for MCT-1 and MCT-2, respectively. This compound exhibits immunosuppressive properties and is utilized in research concerning graft versus host disease and metabolic regulation. Its ability to modulate lactate transport makes it a valuable tool for studying the role of MCTs in various biological processes.
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