Product Data Sheet
AR-C141990
Catalog No. A67488
AR-C141990 functions as a dual inhibitor of CYP2C9 and CYP3A4, exhibiting IC50 values of 16 μM for both enzymes. This compound is recognized for its significant bioactivity, particularly as it inhibits the monocarboxylate transporter MCT1 with a Ki value of 4.8 nM. AR-C141990 is employed in research applications focused on drug metabolism and pharmacokinetics, as well as studies investigating interactions between drugs and metabolic pathways.
Chemical Information
| Catalog Num | A67488 |
|---|---|
| M. Wt | 492.59 |
| Formula | C26H28N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 873327-59-4 |
| Synonyms | |
| SMILES | O=C1N(CC(C)C)C2=C(C(C(N3C[C@H](O)CC3)=O)=C(CC4=CC=NC5=CC=CC=C45)S2)C(N1C)=O |
Biological Activity
| Description | AR-C141990 functions as a dual inhibitor of CYP2C9 and CYP3A4, exhibiting IC50 values of 16 μM for both enzymes. This compound is recognized for its significant bioactivity, particularly as it inhibits the monocarboxylate transporter MCT1 with a Ki value of 4.8 nM. AR-C141990 is employed in research applications focused on drug metabolism and pharmacokinetics, as well as studies investigating interactions between drugs and metabolic pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
