Acevaltrate
Catalog No. A67527

Acevaltrate is a selective inhibitor of Na+/K+ ATPase, demonstrating IC50 values of 22.8 μM in rat kidney tissues and 42.3 μM in brain hemispheres. This compound is valuable for studying ion transport mechanisms and the physiological roles of Na+/K+ ATPase in renal and neurological contexts. Its inhibitory effects make it a suitable tool for exploring potential therapeutic applications in conditions related to dysregulated ion homeostasis.
Chemical Information
| Catalog Num | A67527 |
|---|---|
| M. Wt | 480.50 |
| Formula | C24H32O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 25161-41-5 |
| Synonyms | |
| SMILES | O=C(CC(C)(C)OC(C)=O)O[C@@H]1[C@]2(CO2)[C@]([C@@H]3OC(CC(C)C)=O)([H])C(C(COC(C)=O)=CO3)=C1 |
Biological Activity
| Description | Acevaltrate is a selective inhibitor of Na+/K+ ATPase, demonstrating IC50 values of 22.8 μM in rat kidney tissues and 42.3 μM in brain hemispheres. This compound is valuable for studying ion transport mechanisms and the physiological roles of Na+/K+ ATPase in renal and neurological contexts. Its inhibitory effects make it a suitable tool for exploring potential therapeutic applications in conditions related to dysregulated ion homeostasis. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


