Product Data Sheet

LND 623

Catalog No. A67554

main product photo
LND 623 is a Na+/K+ ATPase inhibitor known for its positive inotropic effects. This aminosteroid compound effectively inhibits Na+/K+ ATPase activity, making it a valuable tool in cardiovascular research. With an LD50 of approximately 45 mg/kg when administered intravenously, LND 623 presents a significantly higher tolerance compared to ouabain, facilitating studies in cardiac function and related therapies.
Chemical Information
Catalog NumA67554
M. Wt481.67
FormulaC27H47NO6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.90520-42-6
Synonyms
SMILESO[C@H]([C@@H]([C@H]([C@H](C)O1)O)O)[C@H]1O[C@H]2CC[C@]3(C)[C@@]4([H])CC[C@]5(C)[C@@H]([C@H](O)C)CC[C@]5(N)[C@]4([H])CC[C@]3([H])C2
Biological Activity
DescriptionLND 623 is a Na+/K+ ATPase inhibitor known for its positive inotropic effects. This aminosteroid compound effectively inhibits Na+/K+ ATPase activity, making it a valuable tool in cardiovascular research. With an LD50 of approximately 45 mg/kg when administered intravenously, LND 623 presents a significantly higher tolerance compared to ouabain, facilitating studies in cardiac function and related therapies.
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