Product Data Sheet
NS3861
Catalog No. A67586
NS3861 is a selective agonist of the heteromeric α3β4 nicotinic acetylcholine receptor (nAChR), exhibiting high-affinity binding with a Ki value of 0.62 nM. This compound also demonstrates varied affinities for other nAChR subtypes, with Ki values of 25 nM for α3β2, 7.8 nM for α4β4, and 55 nM for α4β2. NS3861 is valuable for research focused on synaptic transmission and neuropharmacology, facilitating studies of cholinergic signaling in conditions such as neurodegeneration and addiction.
Chemical Information
| Catalog Num | A67586 |
|---|---|
| M. Wt | 284.22 |
| Formula | C12H14BrNS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 216853-59-7 |
| Synonyms | |
| SMILES | BrC1=C(SC=C1)C2=CC(CCC3C2)N3C |
Biological Activity
| Description | NS3861 is a selective agonist of the heteromeric α3β4 nicotinic acetylcholine receptor (nAChR), exhibiting high-affinity binding with a Ki value of 0.62 nM. This compound also demonstrates varied affinities for other nAChR subtypes, with Ki values of 25 nM for α3β2, 7.8 nM for α4β4, and 55 nM for α4β2. NS3861 is valuable for research focused on synaptic transmission and neuropharmacology, facilitating studies of cholinergic signaling in conditions such as neurodegeneration and addiction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
