Product Data Sheet

ABT-107

Catalog No. A67588

main product photo
ABT-107 is a selective agonist of the α7 neuronal nicotinic receptor (nAChR), known for its neuroprotective properties. This compound has demonstrated effectiveness in protecting against nigrostriatal damage in rodent models, specifically in rats with unilateral 6-hydroxydopamine lesions. ABT-107 is a valuable tool for research applications focusing on neurodegenerative diseases and the role of nicotinic receptors in neurological function.
Chemical Information
Catalog NumA67588
M. Wt320.39
FormulaC19H20N4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.855291-54-2
Synonyms
SMILES[C@H]1(C2CCN(CC2)C1)OC3=CC=C(C4=CC=C(NC=C5)C5=C4)N=N3
Biological Activity
DescriptionABT-107 is a selective agonist of the α7 neuronal nicotinic receptor (nAChR), known for its neuroprotective properties. This compound has demonstrated effectiveness in protecting against nigrostriatal damage in rodent models, specifically in rats with unilateral 6-hydroxydopamine lesions. ABT-107 is a valuable tool for research applications focusing on neurodegenerative diseases and the role of nicotinic receptors in neurological function.
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SHIPPING AND STORAGE
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