Product Data Sheet
TC-2559 difumarate
Catalog No. A67601
TC-2559 difumarate is a centrally active partial agonist targeting the α4β2 subtype of nicotinic acetylcholine receptors (nAChRs), with an EC50 of 0.18 μM. This compound demonstrates selectivity for α4β2 receptors over α2β4, α4β4, and α3β4 receptors, exhibiting EC50 values between 10-30 µM. TC-2559 difumarate is primarily used in research focused on antinociceptive effects and the modulation of CNS activity.
Chemical Information
| Catalog Num | A67601 |
|---|---|
| M. Wt | 438.43 |
| Formula | C20H26N2O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2454492-41-0 |
| Synonyms | |
| SMILES | CCOC1=CN=CC(/C=C/CCNC)=C1.O=C(/C=C/C(O)=O)O.O=C(/C=C/C(O)=O)O |
Biological Activity
| Description | TC-2559 difumarate is a centrally active partial agonist targeting the α4β2 subtype of nicotinic acetylcholine receptors (nAChRs), with an EC50 of 0.18 μM. This compound demonstrates selectivity for α4β2 receptors over α2β4, α4β4, and α3β4 receptors, exhibiting EC50 values between 10-30 µM. TC-2559 difumarate is primarily used in research focused on antinociceptive effects and the modulation of CNS activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
