Product Data Sheet
AR-R17779 hydrochloride
Catalog No. A67603
AR-R17779 hydrochloride is a potent and selective full agonist of the nicotinic acetylcholine receptor (nAChR), demonstrating Ki values of 92 nM for the α7 subtype and 16,000 nM for the α4β2 subtype. This compound has been shown to enhance cognitive functions, such as learning and memory, in rodent models. Additionally, AR-R17779 hydrochloride exhibits anxiolytic properties and is capable of reducing inflammation through the activation of anti-inflammatory cholinergic pathways. Its diverse biological activities make it a valuable tool for research in neurobiology and inflammation.
Chemical Information
| Catalog Num | A67603 |
|---|---|
| M. Wt | 218.68 |
| Formula | C9H15ClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 178419-42-6 |
| Synonyms | |
| SMILES | O=C(NC1)O[C@@]21CN3CCC2CC3.[H]Cl |
Biological Activity
| Description | AR-R17779 hydrochloride is a potent and selective full agonist of the nicotinic acetylcholine receptor (nAChR), demonstrating Ki values of 92 nM for the α7 subtype and 16,000 nM for the α4β2 subtype. This compound has been shown to enhance cognitive functions, such as learning and memory, in rodent models. Additionally, AR-R17779 hydrochloride exhibits anxiolytic properties and is capable of reducing inflammation through the activation of anti-inflammatory cholinergic pathways. Its diverse biological activities make it a valuable tool for research in neurobiology and inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
